twsg1 Phenotypes

Summary

Expression

Phenotypes

XB-GENEPAGE-483444

Gene Symbol: twsg1 Gene Name: twisted gastrulation BMP signaling modulator 1

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: twsg1 assayed (8 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (66 sources): abnormal bone marrow cell morphology/development, abnormal caudal vertebrae morphology, abnormal cervical vertebrae morphology, abnormal craniofacial development, abnormal craniofacial morphology, abnormal foregut morphology, abnormal frontonasal prominence morphology, abnormal intervertebral disk development, abnormal intervertebral disk morphology, abnormal kidney development, abnormal long bone epiphyseal plate morphology, abnormal long bone epiphyseal plate proliferative zone, abnormal oropharynx morphology, abnormal skeleton development, abnormal spleen development, abnormal submandibular gland development, abnormal tail morphology, abnormal telencephalon development, abnormal thoracic vertebrae morphology, abnormal thymus development, abnormal timing of postnatal eyelid opening, abnormal vertebral arch development, abnormal vertebral arch morphology, abnormal vertebral lamina morphology, abnormal vertebral spinous process morphology, absent submandibular gland, agnathia, decreased body length, decreased body mass index, decreased body size, decreased bone mineral content, decreased bone trabecula number, decreased bone volume, decreased caudal vertebrae number, decreased circulating osteocalcin level, decreased double-positive T cell number, decreased erythrocyte cell number, decreased immature B cell number, decreased pre-B cell number, decreased pro-B cell number, decreased spleen white pulp amount, decreased splenocyte number, decreased thymocyte number, decreased trabecular bone volume, decreased width of hypertrophic chondrocyte zone, delayed bone ossification, delayed endochondral bone ossification, disproportionate dwarf, fused first pharyngeal arch, hindlimb paralysis, increased granulocyte number, increased single-positive T cell number, increased thymocyte apoptosis, kinked tail, lethality at weaning, incomplete penetrance, neonatal lethality, incomplete penetrance, perinatal lethality, incomplete penetrance, persistence of notochord tissue, postnatal lethality, complete penetrance, premature death, prenatal lethality, incomplete penetrance, short tail, small first pharyngeal arch, subarachnoid hemorrhage, thin neurocranium, thymus atrophy [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (66 sources): abnormal bone marrow cell morphology/development, abnormal caudal vertebrae morphology, abnormal cervical vertebrae morphology, abnormal craniofacial development, abnormal craniofacial morphology, abnormal foregut morphology, abnormal frontonasal prominence morphology, abnormal intervertebral disk development, abnormal intervertebral disk morphology, abnormal kidney development, [+]