nkx6-1 NK6 homeobox 1
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
|Manual annotations: nkx6-1 manipulated (1 source), nkx6-1 assayed (2 sources)|
|Computed annotations: nkx6-1 assayed (1 source)|
These are short form descriptions of experiments using reagents targeting the gene of interest.
|Xla Wt + nkx6-1 (1 source)|
|Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (14 sources):
abnormal motor capabilities/coordination/movement,
abnormal neuron specification,
abnormal spinal cord interneuron morphology,
decreased insulin secretion,
decreased motor neuron number,
decreased pancreatic alpha cell number,
decreased pancreatic delta cell number,
decreased pancreatic epsilon cell number,
endocrine/exocrine gland phenotype,
homeostasis/metabolism phenotype, increased pancreatic beta cell number, neonatal lethality, complete penetrance, small pancreatic islets[+]