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Summary Expression Phenotypes Gene Literature (114) GO Terms (16) Nucleotides (378) Proteins (53) Interactants (913) Wiki
XB-GENEPAGE-483730

fzd7     frizzled class receptor 7

Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
abnormal histone phosphorylation (5 sources), abnormal foregut morphology (3 sources), abnormal gastrulation (3 sources), abnormal regulation of cell size (3 sources), decreased length of anterior-posterior axis (3 sources), increased size of the cell (3 sources), abnormal bending of anterior-posterior axis (2 sources), abnormal bending of tail (2 sources), abnormal head morphology (2 sources), abnormally edematous foregut (2 sources), absent liver (2 sources), absent stomach (2 sources), decreased size of the dorsal marginal zone (2 sources), increased size of the foregut (2 sources), abnormal Brachet's cleft morphology (1 source), abnormal JNK cascade (1 source), abnormal alimentary system morphology (1 source), abnormal archenteron morphology (1 source), abnormal canonical Wnt signaling pathway (1 source), abnormal cell adhesion (1 source), abnormal cell morphology (1 source), abnormal dorsal trunk (1 source), abnormal endoderm morphology (1 source), abnormal foregut endoderm morphology (1 source), abnormal hindgut morphology (1 source), abnormal incomplete closing of the neural tube (1 source), abnormal tail bud morphology (1 source), abnormal tail morphology (1 source), abnormal whole organism morphology (1 source), abnormally decreased coiling of small intestine (1 source), abnormally decreased length of alimentary system (1 source), abnormally decreased length of intestine (1 source), abnormally delayed closure of blastopore (1 source), abnormally edematous alimentary system (1 source), abnormally edematous pharyngeal region (1 source), absent pancreas (1 source), dead whole organism (1 source), decreased cell adhesion in foregut (1 source), decreased cell population proliferation in foregut endoderm (1 source), decreased length of tail (1 source), decreased size of the actin cytoskeleton (1 source), decreased size of the archenteron (1 source), decreased size of the eye (1 source), decreased size of the heart (1 source), decreased size of the tail (1 source), increased size of the foregut endoderm (1 source)
Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: fzd7 manipulated (24 sources)
Computed annotations: fzd7 assayed (14 sources)
Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + fzd7 MO (11 sources), Xla Wt + fzd7 MO (5 sources), Xla Wt + fzd7 MO (5 sources), Xla Wt + fzd7 MO + sdc4 MO (4 sources), Xla Wt + fzd7 MO (3 sources), Xla Wt + fzd7 MO + sdc4 MO (3 sources), Xtr Wt + fzd7 MO (3 sources), Xla Wt + fzd7 MO (2 sources), Xla Wt + fzd7 MO (2 sources), Xla Wt + fzd7 MO (2 sources), Xla Wt + fzd7 MO + BIO (2 sources), Xla Wt + fzd7 MO + sdc4 MO (2 sources), Xla Wt + fzd7 MO + sdc4 MO (2 sources), Xtr Wt + fzd7 MO (2 sources), Xla Wt + fzd7 MO (1 source), Xla Wt + fzd7 MO (1 source), Xla Wt + fzd7 MO (1 source), Xla Wt + fzd7 MO (1 source), Xla Wt + fzd7 MO + sdc4 MO (1 source), Xla Wt + hsp70:xfz7;hsp70:GFP3 + HS (1 source), Xla Wt + hsp70:xfz7;hsp70:GFP3 + HS (1 source), Xla Wt + hsp70:xfz7;hsp70:GFP3 + HS (1 source), Xla Wt + Mmu.lef1-Mmu.ctnnb1-GR + fzd7 MO + DEX (1 source), Xla Wt + caHsa.MAPK8 + fzd7 MO + DEX (1 source)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (2 sources): kinked tail, short tail