| Monarch Ortholog Phenotypes
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Human (3 sources):
Intraalveolar nodular calcifications,
Progressive pulmonary function impairment,
obsolete Restrictive deficit on pulmonary function testing
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Mouse (19 sources):
abnormal embryo development,
abnormal extraembryonic tissue morphology,
abnormal feces composition,
abnormal intestinal absorption,
abnormal intestine physiology,
abnormal vitamin D level,
abnormal vitelline vascular remodeling,
absent placental labyrinth,
calcified pulmonary alveolus,
decreased embryo size,
decreased physiological sensitivity to xenobiotic,
decreased susceptibility to injury,
embryonic growth arrest,
embryonic lethality between somite formation and embryo turning, incomplete penetrance,
embryonic lethality during organogenesis, complete penetrance,
embryonic lethality, complete penetrance,
failure of chorioallantoic fusion,
failure of initiation of embryo turning,
failure of somite differentiation
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.