akt2 Phenotypes

XB-GENEPAGE-484167

Gene Symbol: akt2 Gene Name: v-akt murine thymoma viral oncogene homolog 2

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (28 sources): Abnormal circulating insulin level, Acanthosis nigricans, Decreased adiponectin level, Decreased serum leptin, Decreased waist to hip ratio, Enlarged tonsils, Gynecomastia, Hemihypertrophy, Hepatic steatosis, Hepatomegaly, Hyperlipidemia, Hypertriglyceridemia, Hypoglycemic coma, Hypoglycemic seizures, Hypoketotic hypoglycemia, Increased hepatic glycogen content, Increased intraabdominal fat, Insulin resistance, Insulin-resistant diabetes mellitus, Large for gestational age, Lipodystrophy, Neonatal hypoglycemia, Nonketotic hypoglycemia, Oligomenorrhea, Polycystic ovaries, Seizure, Truncal obesity, Type II diabetes mellitus [+]
Mouse (23 sources): abnormal bone mineralization, decreased adipocyte glucose uptake, decreased body length, decreased brown adipose tissue mass, decreased circulating glucose level, decreased corpora lutea number, decreased liver triglyceride level, decreased muscle cell glucose uptake, decreased susceptibility to diet-induced obesity, decreased white adipose tissue mass, growth/size/body region phenotype, immune system phenotype, increased T cell derived lymphoma incidence, increased bone mineral content, increased circulating alkaline phosphatase level, increased lean body mass, increased lymphoma incidence, increased pancreatic islet number, increased prepulse inhibition, increased startle reflex, increased theca cell number, increased total body fat amount, premature death [+]
View all ortholog results at Monarch