tcf21 Phenotypes

Summary

Expression

Phenotypes

XB-GENEPAGE-484804

Gene Symbol: tcf21 Gene Name: transcription factor 21

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: tcf21 assayed (1 source)
Computed annotations: tcf21 assayed (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (45 sources): abnormal branching involved in lung morphogenesis, abnormal branching involved in ureteric bud morphogenesis, abnormal glomerular capillary morphology, abnormal heart apex morphology, abnormal heart shape, abnormal kidney blood vessel morphology, abnormal kidney development, abnormal kidney mesenchyme morphology, abnormal kidney morphology, abnormal lung epithelium morphology, abnormal lung vasculature morphology, abnormal ovary topology, abnormal peritubular capillary morphology, abnormal podocyte foot process morphology, abnormal podocyte morphology, abnormal proximal convoluted tubule morphology, abnormal pulmonary acinus morphology, abnormal pulmonary alveolar sac morphology, abnormal renal glomerular capsule morphology, abnormal renal glomerulus morphology, abnormal spleen development, abnormal ureteric bud morphology, abnormal ureteric bud tip morphology, absent proximal convoluted tubule brush border, absent pulmonary alveoli, absent type II pneumocytes, decreased renal glomerulus number, delayed kidney development, dilated respiratory conducting tube, disorganized testis cords, ectopic ovary, impaired branching involved in alveolar sac morphogenesis, impaired branching involved in bronchus morphogenesis, impaired branching involved in ureteric bud morphogenesis, neonatal lethality, complete penetrance, no abnormal phenotype detected, pale kidney, podocyte foot process effacement, primary sex reversal, renal glomerulus atrophy, secondary sex reversal, small kidney, small lung, small lung lobe, thin myocardium [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (45 sources): abnormal branching involved in lung morphogenesis, abnormal branching involved in ureteric bud morphogenesis, abnormal glomerular capillary morphology, abnormal heart apex morphology, abnormal heart shape, abnormal kidney blood vessel morphology, abnormal kidney development, abnormal kidney mesenchyme morphology, abnormal kidney morphology, abnormal lung epithelium morphology, [+]