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Summary Expression Phenotypes Gene Literature (175) GO Terms (17) Nucleotides (57) Proteins (32) Interactants (1013) Wiki
XB-GENEPAGE-485279

wnt1     Wnt family member 1

Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
abnormal foregut epithelium morphology (2 sources), abnormal heart morphology (2 sources), abnormally dorsalized embryo (2 sources), abnormally split primary heart field (2 sources), obsolete duplicated anatomical axis (2 sources), abnormal cell morphology (1 source), abnormal ciliated cell (1 source), abnormal development of alimentary system (1 source), abnormal development of heart (1 source), abnormal establishment of cell polarity (1 source), abnormal foregut endoderm morphology (1 source), abnormal gastrulation (1 source), abnormal liver morphology (1 source), abnormal regulation of cell size (1 source), abnormal tail morphology (1 source), abnormally localised cilium in gastrocoel roof plate (1 source), abnormally ventralized embryo (1 source), decreased length of anterior-posterior axis (1 source), decreased size of the tail (1 source), duplicated head (1 source), increased width of neural plate (1 source), obsolete decreased cilium motility in left-right organizer (1 source), obsolete duplicated anterior-posterior axis (1 source), partially anteriorized embryo (1 source), partially ventralized embryo (1 source)
Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: wnt1 assayed (2 sources)
Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + wnt11b MO (5 sources), Xla Wt + wnt11b (3 sources), Xla Wt + wnt11b MO (3 sources), Xla Wt + Mmu.wnt1del284 (2 sources), Xla Wt + sfrp5 + wnt11 (1 source), Xla Wt + wnt1 (1 source), Xla Wt + wnt11b (1 source), Xla Wt + wnt11b MO (1 source), Xla Wt + wnt11b MO (1 source), Xla Wt + wnt11b MO (1 source), Xla Wt + wnt16 (1 source), Xla Wt + wnt16 + wnt8a (1 source), Xtr Wt + wnt11b MO (1 source)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (39 sources): Abnormal thorax morphology, Abnormality of the nervous system, Basilar impression, Biconcave flattened vertebrae, Biconcave vertebral bodies, Blue sclerae, Bowing of limbs due to multiple fractures, Cerebellar hypoplasia, Decreased calvarial ossification, Dentinogenesis imperfecta, [+]
Mouse (39 sources): abnormal brain white matter morphology, abnormal branching of the mammary ductal tree, abnormal cerebellar cortex morphology, abnormal cerebellum anterior vermis morphology, abnormal cerebellum development, abnormal cranial flexure morphology, abnormal embryo size, abnormal frontal lobe morphology, abnormal hindbrain development, abnormal inferior colliculus morphology, [+]

View all ortholog results at Monarch