Monarch Ortholog Phenotypes
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Mouse (42 sources):
abnormal atrial thrombosis,
abnormal cardiac thrombosis,
abnormal dentate gyrus morphology,
abnormal endocrine pancreas morphology,
abnormal eye development,
abnormal hippocampus CA4 region morphology,
abnormal hippocampus granule cell morphology,
abnormal interventricular septum muscular part morphology,
abnormal lens development,
abnormal liver development,
abnormal lymph circulation,
abnormal lymph organ development,
abnormal myocardial fiber morphology,
abnormal skeletal muscle morphology,
abnormal suckling behavior,
abnormal ventricular thrombosis,
absent retina horizontal cells,
cardiovascular system phenotype,
decreased cardiac muscle contractility,
decreased hepatocyte proliferation,
decreased locomotor activity,
decreased lymphatic vessel endothelial cell number,
decreased survivor rate,
dilated heart,
increased circulating alanine transaminase level,
increased liver triglyceride level,
increased macrophage cell number,
increased pancreatic acinar cell number,
increased susceptibility to age related obesity,
increased total body fat amount,
increased total fat pad weight,
increased total retina thickness,
interventricular septum membranous part aneurysm,
lethality throughout fetal growth and development, complete penetrance,
no abnormal phenotype detected,
postnatal lethality, complete penetrance,
postnatal lethality, incomplete penetrance,
premature death,
small liver,
small pancreas,
thick tricuspid valve cusps,
thin myocardium
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