ddr1 Phenotypes

Phenotypes

XB-GENEPAGE-485345

Gene Symbol: ddr1 Gene Name: discoidin domain receptor tyrosine kinase 1

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: ddr1 assayed (4 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (18 sources): abnormal aorta collagen fibril morphology, abnormal bone mineralization, abnormal cranium morphology, abnormal lactation, abnormal locomotor activation, abnormal mammary gland development, abnormal mammary gland duct morphology, abnormal outer ear morphology, abnormal podocyte slit diaphragm morphology, abnormal renal tubule epithelium morphology, decreased anxiety-related response, erythrocyturia, failure of embryo implantation, homeostasis/metabolism phenotype, increased mammary gland epithelial cell proliferation, increased renal glomerulus basement membrane thickness, preweaning lethality, incomplete penetrance, renal/urinary system phenotype [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (18 sources): abnormal aorta collagen fibril morphology, abnormal bone mineralization, abnormal cranium morphology, abnormal lactation, abnormal locomotor activation, abnormal mammary gland development, abnormal mammary gland duct morphology, abnormal outer ear morphology, abnormal podocyte slit diaphragm morphology, abnormal renal tubule epithelium morphology, [+]