| Monarch Ortholog Phenotypes
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Human (20 sources):
2-3 finger syndactyly,
Abnormal carpal morphology,
Abnormal distal phalanx morphology of finger,
Abnormal fingernail morphology,
Abnormality of the humerus,
Abnormality of the ulna,
Aplasia/Hypoplasia of the radius,
Brachydactyly,
Clinodactyly of the 5th finger,
Elbow dislocation,
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Mouse (31 sources):
abnormal Meckel's cartilage morphology,
abnormal adipose tissue amount,
abnormal artery morphology,
abnormal hindlimb morphology,
abnormal long bone epiphyseal plate morphology,
abnormal middle ear ossicle morphology,
abnormal nail morphology,
abnormal postnatal growth,
abnormal tarsal bone morphology,
absent gonial bone,
absent ilium,
absent sesamoid bone of gastrocnemius,
absent submandibular gland,
bifurcated tongue,
decreased bone volume,
decreased gonadotroph cell number,
decreased thyrotroph cell number,
decreased tympanic ring size,
embryonic lethality during organogenesis, incomplete penetrance,
failure of palatal shelf elevation,
fused phalanges,
increased bone mineral content,
increased width of hypertrophic chondrocyte zone,
neonatal lethality, complete penetrance,
perinatal lethality, complete penetrance,
preweaning lethality, complete penetrance,
short mandible,
small ischium,
small limb buds,
small mandible,
small pubis
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.