| Monarch Ortholog Phenotypes
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Human (20 sources):
Anteverted nares,
Delayed speech and language development,
Depressed nasal bridge,
Downturned corners of mouth,
Dysarthria,
Dysphagia,
Epicanthus,
Esophoria,
Esotropia,
Facial palsy,
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Mouse (29 sources):
abnormal axon guidance,
abnormal blinking,
abnormal buccinator muscle morphology,
abnormal cochlear VIII nucleus morphology,
abnormal craniofacial morphology,
abnormal depressor anguli oris muscle morphology,
abnormal digastric posterior belly morphology,
abnormal facial motor nucleus morphology,
abnormal lower lip morphology,
abnormal masseter muscle morphology,
abnormal neuron differentiation,
abnormal rhombomere 4 morphology,
abnormal temporalis muscle morphology,
abnormal vibrissae reflex,
abnormal zygomaticus muscle morphology,
absent facial muscle,
absent facial nerve,
absent facial nuclei,
absent levator nasolabialis muscle,
behavior/neurological phenotype,
decreased body size,
decreased motor neuron number,
decreased sensory neuron number,
facial muscle degeneration,
neonatal lethality, incomplete penetrance,
nervous system phenotype,
no abnormal phenotype detected,
postnatal lethality, incomplete penetrance,
small facial motor nucleus
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.