hdac2 Phenotypes

Phenotypes

XB-GENEPAGE-485806

Gene Symbol: hdac2 Gene Name: histone deacetylase 2

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: hdac2 assayed (2 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (33 sources): abnormal dentate gyrus morphology, abnormal eye electrophysiology, abnormal fetal cardiomyocyte proliferation, abnormal hippocampus CA1 region morphology, abnormal hippocampus pyramidal cell morphology, abnormal intestinal mucosa morphology, abnormal large intestine crypts of Lieberkuhn morphology, abnormal myocardial fiber physiology, abnormal myocardium compact layer morphology, abnormal myocardium layer morphology, abnormal total retina thickness, cardiovascular system phenotype, decreased birth body size, decreased body size, decreased brain weight, decreased intestine length, decreased survivor rate, decreased susceptilbility to retina ischemic injury, diffuse Z line, embryonic lethality during organogenesis, incomplete penetrance, enhanced contextual conditioning behavior, enhanced long term potentiation, immune system phenotype, increased cardiomyocyte apoptosis, insensitivity to growth hormone, neonatal lethality, complete penetrance, no abnormal phenotype detected, perinatal lethality, incomplete penetrance, postnatal lethality, incomplete penetrance, prenatal lethality, incomplete penetrance, reduced fertility, thick interventricular septum, thick ventricular wall [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (33 sources): abnormal dentate gyrus morphology, abnormal eye electrophysiology, abnormal fetal cardiomyocyte proliferation, abnormal hippocampus CA1 region morphology, abnormal hippocampus pyramidal cell morphology, abnormal intestinal mucosa morphology, abnormal large intestine crypts of Lieberkuhn morphology, abnormal myocardial fiber physiology, abnormal myocardium compact layer morphology, abnormal myocardium layer morphology, [+]