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Summary Expression Phenotypes Gene Literature (42) GO Terms (10) Nucleotides (1698) Proteins (71) Interactants (813) Wiki

tpm1     tropomyosin 1

Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: tpm1 assayed (6 sources)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (12 sources): Abnormality of neutrophils, Congestive heart failure, Dilated cardiomyopathy, EMG abnormality, Elevated circulating creatine kinase concentration, Hypertrophic cardiomyopathy, Lipoatrophy, Mitral regurgitation, Myopathy, Palmoplantar keratoderma, [+]
Mouse (36 sources): abnormal atrial thrombosis, abnormal bronchiole morphology, abnormal calcium ion homeostasis, abnormal cardiac muscle contractility, abnormal cardiac muscle relaxation, abnormal diastolic filling velocity, abnormal heart ventricle pressure, abnormal myocardial fiber morphology, abnormal myocardial fiber physiology, abnormal response to exercise, [+]

View all ortholog results at Monarch