Monarch Ortholog Phenotypes
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Mouse (45 sources):
abnormal S-shaped body morphology,
abnormal T cell differentiation,
abnormal channel response,
abnormal circulating alkaline phosphatase level,
abnormal comma shaped body morphology,
abnormal developmental patterning,
abnormal digestion,
abnormal embryo morphology,
abnormal hair follicle melanocyte morphology,
abnormal kidney development,
abnormal magnesium ion homeostasis,
abnormal nephron morphogenesis,
abnormal renal tubule morphology,
abnormal rostrocaudal coat patterning,
abnormal thymus cell ratio,
abnormal thymus corticomedullary boundary morphology,
abnormal thymus medulla morphology,
abnormal thymus morphology,
absent hair follicle melanin granules,
decreased embryo size,
decreased erythrocyte magnesium level,
decreased melanocyte number,
decreased renal glomerulus number,
decreased sensory neuron number,
decreased thymocyte number,
dilated renal tubules,
embryonic growth arrest,
embryonic lethality between implantation and somite formation, complete penetrance,
embryonic lethality prior to tooth bud stage,
embryonic lethality, complete penetrance,
hindlimb paralysis,
impaired limb coordination,
increased circulating alkaline phosphatase level,
increased circulating amylase level,
increased sensitivity to induced morbidity/mortality,
increased susceptibility to type IV hypersensitivity reaction,
irregularly shaped pupil,
limb grasping,
no abnormal phenotype detected,
paresis,
prenatal lethality, complete penetrance,
preweaning lethality, complete penetrance,
renal/urinary system phenotype,
small dorsal root ganglion,
small kidney
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