cd44 Phenotypes

Summary

Expression

Phenotypes

XB-GENEPAGE-487546

Gene Symbol: cd44 Gene Name: CD44 molecule (Indian blood group)

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: cd44 assayed (2 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (76 sources): abnormal CD4-positive, alpha beta T cell morphology, abnormal CD4-positive, alpha-beta T cell physiology, abnormal CD8-positive, alpha beta T cell morphology, abnormal T-helper 1 physiology, abnormal T-helper 2 physiology, abnormal cell morphology, abnormal circulating chemokine level, abnormal circulating cytokine level, abnormal definitive hematopoiesis, abnormal epidermal lamellar body morphology, abnormal involution of the mammary gland, abnormal leukocyte adhesion, abnormal leukocyte migration, abnormal lipid level, abnormal miniature excitatory postsynaptic currents, abnormal mitochondrial crista morphology, abnormal osteoclast differentiation, abnormal physiological neovascularization, abnormal response to cardiac infarction, abnormal response to infection, abnormal uterus morphology, abnormal vascular endothelial cell morphology, abnormal vascular endothelial cell physiology, abnormal vascular smooth muscle physiology, abnormal vasculogenesis, choroidal neovascularization, decreased CD4-positive, alpha beta T cell number, decreased T cell proliferation, decreased activation-induced cell death of T cells, decreased acute inflammation, decreased alpha-beta T cell number, decreased angiogenesis, decreased blood urea nitrogen level, decreased central memory CD4-positive, alpha-beta T cell number, decreased central memory CD8 positive, alpha-beta T cell number, decreased cholesterol level, decreased circulating tumor necrosis factor level, decreased effector memory CD4-positive, alpha-beta T cell number, decreased fibroblast proliferation, decreased mast cell histamine storage, decreased mast cell number, decreased myocardial infarct size, decreased sensitivity to induced cell death, decreased susceptibility to experimental autoimmune encephalomyelitis, decreased susceptibility to induced arthritis, decreased susceptibility to kidney reperfusion injury, decreased susceptibility to type IV hypersensitivity reaction, decreased transforming growth factor beta level, decreased tumor growth/size, delayed wound healing, digestive/alimentary phenotype, enhanced coordination, hematopoietic system phenotype, immune system phenotype, impaired leukocyte tethering or rolling, impaired macrophage phagocytosis, impaired natural killer cell mediated cytotoxicity, impaired neutrophil recruitment, impaired skin barrier function, impaired wound healing, increased acute inflammation, increased circulating interferon-gamma level, increased circulating interleukin-2 level, increased circulating tumor necrosis factor level, increased diameter of tibia, increased interleukin-1 beta secretion, increased interleukin-10 secretion, increased interleukin-6 secretion, increased mean systemic arterial blood pressure, increased mitochondrial size, increased sensitivity to induced morbidity/mortality, increased susceptibility to induced arthritis, increased susceptibility to parasitic infection, increased tumor necrosis factor secretion, no abnormal phenotype detected, thin epidermis [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (76 sources): abnormal CD4-positive, alpha beta T cell morphology, abnormal CD4-positive, alpha-beta T cell physiology, abnormal CD8-positive, alpha beta T cell morphology, abnormal T-helper 1 physiology, abnormal T-helper 2 physiology, abnormal cell morphology, abnormal circulating chemokine level, abnormal circulating cytokine level, abnormal definitive hematopoiesis, abnormal epidermal lamellar body morphology, [+]