il1r1 Phenotypes

Summary

Expression

Phenotypes

XB-GENEPAGE-487651

Gene Symbol: il1r1 Gene Name: interleukin 1 receptor type 1 gene 1

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: il1r1 assayed (3 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (49 sources): abnormal cell death, abnormal food intake, abnormal lean body mass, abnormal microglial cell activation, abnormal response/metabolism to endogenous compounds, abnormal vascular wound healing, decreased T cell proliferation, decreased anxiety-related response, decreased blood urea nitrogen level, decreased circulating interleukin-18 level, decreased circulating interleukin-6 level, decreased circulating serum amyloid protein level, decreased eosinophil cell number, decreased incidence of tumors by chemical induction, decreased interleukin-6 secretion, decreased locomotor activity, decreased susceptibility to autoimmune diabetes, decreased susceptibility to experimental autoimmune uveoretinitis, decreased susceptibility to induced arthritis, decreased susceptibility to kidney reperfusion injury, decreased susceptibility to type IV hypersensitivity reaction, decreased transforming growth factor beta level, decreased tumor necrosis factor secretion, dental pulp necrosis, enhanced contextual conditioning behavior, enhanced wound healing, homeostasis/metabolism phenotype, immune system phenotype, impaired febrile response, increased abdominal fat pad weight, increased body length, increased body mass index, increased circulating insulin-like growth factor I level, increased circulating interleukin-1 beta level, increased circulating interleukin-18 level, increased gonadal fat pad weight, increased growth rate, increased inguinal fat pad weight, increased liver weight, increased mesenteric fat pad weight, increased percent body fat/body weight, increased respiratory quotient, increased retroperitoneal fat pad weight, increased susceptibility to age related obesity, increased susceptibility to bacterial infection induced morbidity/mortality, increased susceptibility to induced arthritis, increased total body fat amount, integument phenotype, no abnormal phenotype detected [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (49 sources): abnormal cell death, abnormal food intake, abnormal lean body mass, abnormal microglial cell activation, abnormal response/metabolism to endogenous compounds, abnormal vascular wound healing, decreased T cell proliferation, decreased anxiety-related response, decreased blood urea nitrogen level, decreased circulating interleukin-18 level, [+]