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Summary Expression Phenotypes Gene Literature (12) GO Terms (2) Nucleotides (40) Proteins (22) Interactants (140) Wiki

casp8     caspase 8

Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: casp8 assayed (6 sources)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (60 sources): Abdominal distention, Abdominal pain, Abnormal rectum morphology, Abnormality of metabolism/homeostasis, Abnormality of the hepatic vasculature, Abnormality of the liver, Anasarca, Anemia, Anorexia, Ascites, [+]
Mouse (62 sources): abnormal CD8-positive, alpha-beta T cell physiology, abnormal T cell activation, abnormal T cell proliferation, abnormal T cell subpopulation ratio, abnormal adaptive immunity, abnormal blood cell morphology/development, abnormal cell death, abnormal embryonic hematopoiesis, abnormal heart shape, abnormal hematopoietic system morphology/development, [+]

View all ortholog results at Monarch