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XB-GENEPAGE-489345
rab11a RAB11A, member RAS oncogene family
Anatomical Phenotypes
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abnormal tracheoesophageal septum (4 sources), decreased size of the trachea (3 sources), abnormal development of transient tracheoesophageal septum (2 sources), abnormal tracheoesophageal fold morphology (2 sources), abnormal development of blastopore (1 source), abnormal development of upper blastopore lip (1 source), abnormal esophagus morphology (1 source), abnormally localised mitotic spindle (1 source), abnormal trachea morphology (1 source) |
Expression Phenotypes
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Manual annotations: rab11a manipulated (5 sources), rab11a assayed (7 sources) |
Diseases
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esophageal atresia/tracheoesophageal fistula (7AP sources, 2 EP sources), esophageal atresia (3AP sources) |
Experiments (Reagents)
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Xtr Wt + rab11a CRISPR (5 sources), Xla Wt + rab11a MO (3 sources), Xla Wt + dnrab11 (2 sources), Xla Wt + Doxycycline hyclate + Tg(hhex:rtTA;TRE:dnRab11a-GFP) (1 source), Xla Wt + rab11a CRISPR (1 source), Xla Wt + rab11a MO (1 source) |
Monarch Ortholog Phenotypes
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Mouse (29 sources): abnormal crypts of Lieberkuhn morphology, abnormal egg cylinder morphology, abnormal embryo size, abnormal embryo turning, abnormal intestinal epithelium morphology, abnormal intestinal goblet cell morphology, abnormal intestine physiology, abnormal mean corpuscular hemoglobin, abnormal small intestinal crypt cell proliferation, absent head fold, [+] |