wdr1 Phenotypes

Phenotypes

XB-GENEPAGE-489896

Gene Symbol: wdr1 Gene Name: WD repeat domain 1

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: wdr1 assayed (2 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (29 sources): abnormal T wave, abnormal erythropoiesis, abnormal eye anterior chamber depth, abnormal megakaryocyte morphology, abnormal myelopoiesis, abnormal myocardial fiber morphology, abnormal myocardium layer morphology, abnormal osteoclast physiology, abnormal platelet alpha-granule morphology, abnormal platelet dense granule morphology, abnormal thrombopoiesis, cardiac hypertrophy, decreased body size, decreased ventricle muscle contractility, ear inflammation, embryonic lethality between implantation and somite formation, incomplete penetrance, embryonic lethality during organogenesis, complete penetrance, embryonic lethality prior to organogenesis, enlarged myocardial fiber, epidermal hyperplasia, increased heart weight, increased neutrophil cell number, increased osteoclast cell number, no abnormal phenotype detected, postnatal lethality, incomplete penetrance, premature death, preweaning lethality, complete penetrance, prolonged P wave, prolonged ST segment [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (29 sources): abnormal T wave, abnormal erythropoiesis, abnormal eye anterior chamber depth, abnormal megakaryocyte morphology, abnormal myelopoiesis, abnormal myocardial fiber morphology, abnormal myocardium layer morphology, abnormal osteoclast physiology, abnormal platelet alpha-granule morphology, abnormal platelet dense granule morphology, [+]