Recurrent infection of the gastrointestinal tract, Recurrent respiratory infections, Sparse hair

abnormal marginal zone B cell morphology, abnormal myelopoiesis, abnormal skin condition, abnormal T cell activation, abnormal tumor necrosis factor level, absent spleen germinal center, acanthosis, autoimmune response, chronic inflammation, decreased B-2 B cell number, decreased B cell proliferation, decreased body size, decreased CD4-positive, alpha-beta memory T cell number, decreased CD4-positive, alpha beta T cell number, decreased double-negative T cell number, decreased double-positive T cell number, decreased follicular B cell number, decreased IgG1 level, decreased IgG2b level, decreased marginal zone B cell number, decreased mature B cell number, decreased Peyer's patch number, decreased regulatory T cell number, decreased T cell proliferation, decreased thymocyte number, decreased transitional stage T2 B cell number, dermatitis, flaky skin, hematopoietic system phenotype, increased activated T cell number, increased activation-induced B cell apoptosis, increased anti-insulin autoantibody level, increased anti-nuclear antigen antibody level, increased B cell proliferation, increased bone marrow cell number, increased circulating interleukin-17 level, increased circulating interleukin-1 alpha level, increased circulating tumor necrosis factor level, increased double-positive T cell number, increased granulocyte number, increased immature B cell number, increased macrophage cell number, increased memory T cell number, increased pre-B cell number, increased pro-B cell number, increased single-positive T cell number, increased susceptibility to bacterial infection induced morbidity/mortality, increased T cell apoptosis, increased T cell proliferation, increased thymocyte number, no abnormal phenotype detected, postnatal lethality, complete penetrance, premature death, small Peyer's patches, small spleen, spleen atrophy, thymus atrophy