Hypertelorism, Macrocephaly, Medulloblastoma, Medulloepithelioma, Multinodular goiter, Nephroblastoma, Ovarian neoplasm, Ovarian thecoma, Overgrowth, Papillary thyroid carcinoma, Pilomatrixoma, Pleuropulmonary blastoma, Renal cell carcinoma, Rhabdomyosarcoma, Sertoli cell neoplasm, Testicular seminoma, Thyroid carcinoma, Thyroid nodule

abnormal craniofacial morphology, abnormal cytotoxic T cell physiology, abnormal dorsal root ganglion morphology, abnormal effector T cell morphology, abnormal efferent ductules of testis morphology, abnormal embryo development, abnormal epididymis epithelium morphology, abnormal epididymis morphology, abnormal female meiosis, abnormal fetal cardiomyocyte morphology, abnormal first pharyngeal arch morphology, abnormal forelimb morphology, abnormal germinal center B cell physiology, abnormal granulocyte differentiation, abnormal hair cycle catagen phase, abnormal hair follicle bulge morphology, abnormal hair follicle development, abnormal hair follicle inner root sheath morphology, abnormal hair follicle morphology, abnormal hair follicle orientation, abnormal hair follicle regression, abnormal heart echocardiography feature, abnormal hindlimb morphology, abnormal humoral immune response, abnormal immunoglobulin V(D)J recombination, abnormal kidney morphology, abnormal limb development, abnormal lung development, abnormal lung epithelium morphology, abnormal lung-associated mesenchyme development, abnormal lymph node cell ratio, abnormal male germ cell apoptosis, abnormal megakaryocyte differentiation, abnormal megakaryocyte morphology, abnormal meiotic spindle morphology, abnormal mitosis, abnormal myocardial fiber morphology, abnormal myocardium layer morphology, abnormal oocyte morphology, abnormal oviduct morphology, abnormal oviduct transport, abnormal positive T cell selection, abnormal pregnancy, abnormal regulatory T cell morphology, abnormal regulatory T cell physiology, abnormal renal corpuscle morphology, abnormal renal glomerulus morphology, abnormal renal tubule epithelial cell primary cilium morphology, abnormal retina layer morphology, abnormal retina photoreceptor morphology, abnormal sarcomere morphology, abnormal seminiferous tubule epithelium morphology, abnormal skeleton development, abnormal skin appearance, abnormal spermatid morphology, abnormal splenic cell ratio, abnormal superovulation, abnormal sympathetic ganglion morphology, abnormal thymus cortex morphology, abnormal thymus development, abnormal thymus epithelium morphology, abnormal thymus involution, abnormal thymus medulla morphology, abnormal thymus morphology, abnormal thymus physiology, abnormal uterus morphology, abnormal ventricular thrombosis, abnormal vibrissa morphology, abnormal vitelline vascular remodeling, absent memory B cells, absent plasma cells, absent vitelline blood vessels, arrested B cell differentiation, blood vessel inflammation, decreased CD4-positive, alpha beta T cell number, decreased CD8-positive, naive alpha-beta T cell number, decreased T cell proliferation, decreased a-wave amplitude, decreased b-wave amplitude, decreased body size, decreased cardiac muscle contractility, decreased cell proliferation, decreased circulating progesterone level, decreased embryo size, decreased endometrial gland number, decreased germinal center B cell number, decreased hair follicle cell proliferation, decreased hair follicle number, decreased immature B cell number, decreased kidney collecting duct number, decreased kidney weight, decreased locomotor activity, decreased male germ cell number, decreased mature B cell number, decreased osteoblast cell number, decreased ovary weight, decreased ovulation rate, decreased pre-B cell number, decreased red blood cell distribution width, decreased regulatory T cell number, decreased renal glomerular filtration rate, decreased single-positive T cell number, decreased spleen weight, decreased susceptibility to Riboviria infection, decreased susceptibility to kidney reperfusion injury, decreased testis weight, decreased thymocyte number, decreased urine osmolality, decreased uterus weight, delayed endochondral bone ossification, delayed hair appearance, dilated efferent ductule of testis, dilated heart left ventricle, dilated renal glomerular capsule, dilated renal tubules, disorganized myocardium, disorganized retina layers, early cellular replicative senescence, ectopic Sertoli cells, embryonic growth arrest, embryonic lethality between implantation and somite formation, complete penetrance, embryonic lethality during organogenesis, complete penetrance, embryonic lethality during organogenesis, incomplete penetrance, embryonic lethality prior to organogenesis, embryonic lethality prior to tooth bud stage, embryonic lethality, complete penetrance, enlarged lung, enlarged lymph nodes, epidermal cyst, epidermal hyperplasia, failure of embryo implantation, hair follicle degeneration, hematopoietic system phenotype, homeostasis/metabolism phenotype, immune system phenotype, impaired hematopoiesis, increased B-1 B cell number, increased T cell apoptosis, increased apoptosis, increased bone marrow cell number, increased cardiomyocyte apoptosis, increased central memory CD8 positive, alpha-beta T cell number, increased compact bone volume, increased effector memory CD4-positive, alpha-beta T cell number, increased effector memory CD8-positive, alpha-beta T cell number, increased epididymal epithelium cell proliferation, increased facial tumor incidence, increased fluid intake, increased gamma-delta T cell number, increased hemolymphoid system tumor incidence, increased kidney apoptosis, increased kidney cell proliferation, increased mesenchymal cell proliferation involved in lung development, increased myeloid sarcoma incidence, increased pro-B cell number, increased susceptibility to Herpesvirales infection, increased susceptibility to Riboviria infection, increased susceptibility to induced arthritis, integument phenotype, lethality throughout fetal growth and development, complete penetrance, loss of vibrissae, no abnormal phenotype detected, pale kidney, pericardial edema, perinatal lethality, complete penetrance, perinatal lethality, incomplete penetrance, postnatal lethality, complete penetrance, postnatal lethality, incomplete penetrance, premature death, preweaning lethality, complete penetrance, progressive hair loss, renal/urinary system phenotype, reproductive system phenotype, retina gliosis, retina photoreceptor degeneration, seminiferous tubule degeneration, short oviduct, short rostral-caudal axis, short uterine horn, small epididymis, small hair follicle bulb, small hair follicles, small liver, small lung lobe, small seminiferous tubules, small uterus, testis degeneration, thin myometrium, thin retina outer nuclear layer, vision/eye phenotype