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Summary Expression Phenotypes Gene Literature (33) GO Terms (40) Nucleotides (211) Proteins (48) Interactants (501) Wiki
XB-GENEPAGE-491432

pten     phosphatase and tensin homolog

Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
abnormal brain morphology (1 source)
Diseases
Diseases from the human disease ontology (DO) manually associated with phenotypes from disease models. Sources are grouped by anatomical (AP) and expression (EP) phenotypes.
glioblastoma (1AP source)
Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting the gene of interest.
Xtr Wt + rb1 CRISPR + rbl1 CRISPR + tp53 CRISPR + pten CRISPR (1 source)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (266 sources): Abdominal wall muscle weakness, Abnormal cerebellum morphology, Abnormal dental enamel morphology, Abnormal form of the vertebral bodies, Abnormal large intestine morphology, Abnormal lung lobation, Abnormal penis morphology, Abnormal pupil morphology, Abnormal subcutaneous fat tissue distribution, Abnormality of cardiovascular system morphology, [+]
Mouse (403 sources): Mallory bodies, Purkinje cell degeneration, abnormal B cell negative selection, abnormal Bergmann glial cell differentiation, abnormal Bergmann glial cell morphology, abnormal CD8-positive, alpha-beta T cell physiology, abnormal CNS synaptic transmission, abnormal Paneth cell morphology, abnormal Purkinje cell dendrite morphology, abnormal Purkinje cell morphology, [+]

View all ortholog results at Monarch