hap1 Phenotypes

Phenotypes

XB-GENEPAGE-493039

Gene Symbol: hap1 Gene Name: huntingtin-associated protein 1

Anatomical Phenotypes Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
abnormal head morphology (1 source), abnormal tail morphology (1 source), abnormally ruffled dorsal fin (1 source), decreased length of anterior-posterior axis (1 source)

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: hap1 assayed (8 sources)

Experiments (Reagents) These are short form descriptions of experiments using reagents targeting the gene of interest.
Xtr Wt + hap1 MO (2 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (23 sources): abnormal cerebral cortex morphology, abnormal embryo size, abnormal fasting circulating glucose level, abnormal neurite morphology, abnormal neuron proliferation, abnormal paraventricular hypothalamic nucleus morphology, abnormal suckling behavior, abnormal ventromedial hypothalamic nucleus morphology, abnormal vesicle-mediated transport, absent gastric milk in neonates, behavior/neurological phenotype, decreased body size, decreased brain size, decreased brain weight, decreased coping response, decreased food intake, decreased locomotor activity, impaired neuron differentiation, postnatal lethality, complete penetrance, postnatal lethality, incomplete penetrance, preweaning lethality, complete penetrance, slow postnatal weight gain, thin cerebral cortex [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (23 sources): abnormal cerebral cortex morphology, abnormal embryo size, abnormal fasting circulating glucose level, abnormal neurite morphology, abnormal neuron proliferation, abnormal paraventricular hypothalamic nucleus morphology, abnormal suckling behavior, abnormal ventromedial hypothalamic nucleus morphology, abnormal vesicle-mediated transport, absent gastric milk in neonates, [+]