cdk12 Phenotypes

XB-GENEPAGE-493307

Gene Symbol: cdk12 Gene Name: cyclin-dependent kinase 12

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: cdk12 assayed (2 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (16 sources): abnormal embryo size, abnormal hindbrain development, abnormal inner cell mass morphology, abnormal midbrain development, abnormal trophoblast giant cell morphology, chromosomal instability, decreased circulating glucose level, decreased erythrocyte cell number, decreased hematocrit, decreased hemoglobin content, embryonic lethality between implantation and somite formation, complete penetrance, embryonic lethality prior to organogenesis, increased apoptosis, increased heart weight, increased red blood cell distribution width, preweaning lethality, complete penetrance [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (16 sources): abnormal embryo size, abnormal hindbrain development, abnormal inner cell mass morphology, abnormal midbrain development, abnormal trophoblast giant cell morphology, chromosomal instability, decreased circulating glucose level, decreased erythrocyte cell number, decreased hematocrit, decreased hemoglobin content, [+]