Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Phenotypes Gene Literature (95) GO Terms (7) Nucleotides (688) Proteins (43) Interactants (665) Wiki
XB-GENEPAGE-493936

acta2     actin, alpha 2, smooth muscle, aorta

Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: acta2 assayed (12 sources)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (56 sources): Abdominal aortic aneurysm, Abnormal aortic morphology, Abnormal left ventricular function, Abnormal sternum morphology, Abnormality iris morphology, Abnormality of connective tissue, Aortic aneurysm, Aortic dissection, Aortic regurgitation, Aortic root aneurysm, [+]
Mouse (8 sources): abnormal aorta elastic tissue morphology, abnormal blood flow velocity, abnormal cone electrophysiology, abnormal rod electrophysiology, abnormal systemic arterial blood pressure, decreased systemic arterial systolic blood pressure, decreased vasoconstriction, increased vascular permeability

View all ortholog results at Monarch