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XB-GENEPAGE-495118
fus FUS RNA binding protein
Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology
covering anatomical, gene ontology, and neurobehavioral phenotypes.
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| abnormal animal hemisphere morphology (1 source), abnormal gastrulation (1 source), abnormal marginal zone morphology (1 source), abnormal swimming behavior (1 source), abnormally increased number of apoptotic cell (1 source), absent blastopore (1 source), absent swimming behavior (1 source) |
| Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.
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| Manual annotations: fus manipulated (4 sources) |
| Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting
the gene of interest.
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| Xla Wt + fus MO (8 sources), Xla Wt + fus MO (2 sources) |
| Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
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| Human (38 sources): Abnormal pyramidal sign, Abnormal respiratory system physiology, Abnormal upper motor neuron morphology, Abnormality of the bladder, Agitation, Amyotrophic lateral sclerosis, Anxiety, Decreased muscle mass, Degeneration of anterior horn cells, Depression, [+] |
| Mouse (25 sources): abnormal chromosome morphology, abnormal embryo size, abnormal hippocampus pyramidal cell morphology, abnormal male meiosis, abnormal neuromuscular synapse morphology, abnormal prepulse inhibition, abnormal respiratory quotient, abnormal suckling behavior, aneuploidy, decreased body size, [+] |
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View all ortholog results at Monarch |