id3 inhibitor of DNA binding 3, HLH protein
Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
|decreased length of anterior-posterior axis (2 sources), abnormally neoplastic epidermis (1 source), decreased size of the head (1 source)|
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
|Manual annotations: id3 assayed (1 source)|
|Computed annotations: id3 assayed (7 sources)|
These are short form descriptions of experiments using reagents targeting the gene of interest.
|Xtr Wt + id3 MO (1 source), Xtr Wt + id3 MO (1 source)|
|Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (17 sources):
abnormal T cell differentiation,
abnormal double-positive T cell morphology,
decreased B cell proliferation,
decreased CD4-positive, alpha beta T cell number,
decreased thymocyte number,
immune system phenotype,
increased CD4-positive, alpha-beta memory T cell number,
increased CD8-positive, alpha-beta memory T cell number,
increased T follicular helper cell number,
increased autoantibody level, increased gamma-delta T cell number, lacrimal gland inflammation, no abnormal phenotype detected, reproductive system phenotype, salivary gland inflammation, submandibular gland inflammation[+]