cplx1 Phenotypes

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Phenotypes

Gene Literature (1)

Nucleotides (230)

Interactants (17)

XB-GENEPAGE-5815522

Gene Symbol: cplx1 Gene Name: complexin 1

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: cplx1 assayed (2 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (34 sources): Abnormal facial shape, Absent speech, Aggressive behavior, Attention deficit hyperactivity disorder, Bilateral tonic-clonic seizure, Cerebral cortical atrophy, Delayed ability to walk, Delayed fine motor development, Developmental regression, Dysarthria, EEG with irregular generalized spike and wave complexes, Epileptic encephalopathy, Febrile seizure (within the age range of 3 months to 6 years), Feeding difficulties, Focal-onset seizure, Generalized hypotonia, Generalized myoclonic seizure, Generalized non-motor (absence) seizure, Global developmental delay, Hypertelorism, Inability to walk, Intellectual disability, Intellectual disability, mild, Irritability, Language impairment, Leber optic atrophy, Long philtrum, Mental deterioration, Midface retrusion, Myoclonus, Overlapping toe, Photosensitive tonic-clonic seizure, Seizure, Thin upper lip vermilion [+]
Mouse (15 sources): abnormal auditory brainstem response waveform shape, abnormal excitatory postsynaptic currents, abnormal hearing electrophysiology, abnormal miniature excitatory postsynaptic currents, abnormal neuron physiology, abnormal paired-pulse inhibition, abnormal sexual interaction, asthenozoospermia, decreased body size, impaired acrosome reaction, impaired fertilization, increased or absent threshold for auditory brainstem response, premature death, reproductive system phenotype, sporadic seizures [+]
View all ortholog results at Monarch