| Monarch Ortholog Phenotypes
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Human (16 sources):
Abdominal distention,
Abnormal cerebral vascular morphology,
Anemia,
Atrial septal defect,
Edema,
Facial edema,
Lymphedema,
Nonimmune hydrops fetalis,
Pericardial effusion,
Peripheral arteriovenous fistula,
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Mouse (12 sources):
abnormal angiogenesis,
abnormal anterior cardinal vein morphology,
abnormal endocardium morphology,
abnormal vein development,
abnormal vitelline vascular remodeling,
absent myocardial trabeculae,
embryonic growth retardation,
embryonic lethality during organogenesis, complete penetrance,
failure of heart looping,
failure of vascular branching,
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.