| Monarch Ortholog Phenotypes
|
Human (26 sources):
Abnormality of chromosome stability,
Abnormality of neutrophils,
Agammaglobulinemia,
Anemia,
Cellular immunodeficiency,
Communicating hydrocephalus,
Decreased circulating antibody level,
Depressed nasal bridge,
Epicanthus,
Flat face,
Global developmental delay,
Hypertelorism,
Immunodeficiency,
Intellectual disability,
Low-set ears,
Lymphopenia,
Macrocephaly,
Macroglossia,
Malabsorption,
Micrognathia,
Motor delay,
Protruding tongue,
Recurrent infections,
Recurrent respiratory infections,
Short stature,
Umbilical hernia
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Mouse (36 sources):
abnormal DNA methylation,
abnormal DNA methylation during gametogenesis,
abnormal chromosome morphology,
abnormal chromosome number,
abnormal kidney morphology,
abnormal locomotor activation,
abnormal meiosis,
abnormal proximal convoluted tubule morphology,
abnormal renal tubule morphology,
abnormal thoracic vertebrae morphology,
arrest of male meiosis,
decreased IgG1 level,
decreased birth weight,
decreased cell proliferation,
decreased cellular sensitivity to gamma-irradiation,
decreased embryo weight,
decreased fetal weight,
decreased granulocyte number,
decreased male germ cell number,
decreased testis weight,
delayed bone ossification,
delayed endochondral bone ossification,
dilated renal tubules,
increased CD8-positive, alpha-beta T cell number,
increased double-negative T cell number,
increased male germ cell apoptosis,
increased renal tubule apoptosis,
neonatal lethality, complete penetrance,
paternal imprinting,
perinatal lethality, incomplete penetrance,
postnatal lethality, incomplete penetrance,
premature aging,
preweaning lethality, complete penetrance,
small kidney,
small spleen,
small thymus
[+]
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View all ortholog results at Monarch
|
These phenotypes are associated with this gene with a has phenotype relation via Monarch.