stat5b Phenotypes

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Phenotypes

Gene Literature (5)

Nucleotides (84)

Interactants (70)

XB-GENEPAGE-5913742

Gene Symbol: stat5b Gene Name: signal transducer and activator of transcription 5B

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: stat5b assayed (4 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (3 sources): Decreased response to growth hormone stimulation test, Respiratory distress, Severe short stature
Mouse (48 sources): abnormal T cell subpopulation ratio, abnormal acute inflammation, abnormal branching of the mammary ductal tree, abnormal double-negative T cell morphology, abnormal fat pad morphology, abnormal leukopoiesis, abnormal mammary gland alveolus morphology, abnormal mammary gland development, abnormal mammary gland growth during lactation, abnormal mammary gland physiology, abnormal milk ejection, abnormal miscarriage rate, abnormal neutrophil differentiation, abnormal proerythroblast morphology, decreased T cell proliferation, decreased body length, decreased cell proliferation, decreased circulating insulin-like growth factor I level, decreased erythrocyte cell number, decreased hematocrit, decreased hemoglobin content, decreased insulin secretion, decreased lean body mass, decreased mean corpuscular hemoglobin, decreased oxygen consumption, decreased splenocyte number, decreased thymocyte number, decreased urine major urinary protein level, disorganized pancreatic islets, hypolactation, impaired adaptive thermogenesis, impaired natural killer cell mediated cytotoxicity, increased apoptosis, increased circulating glucose level, increased circulating growth hormone level, increased circulating interleukin-17 level, increased circulating iron level, increased interleukin-17 secretion, increased lean body mass, increased mammary gland apoptosis, increased percent body fat/body weight, increased red blood cell distribution width, increased total body fat amount, increased total fat pad weight, lactation failure, microcytosis, no abnormal phenotype detected, pale liver [+]
View all ortholog results at Monarch