gcgr Phenotypes

Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Phenotypes

Gene Literature (7)

Nucleotides (79)

Interactants (17)

XB-GENEPAGE-5918475

Gene Symbol: gcgr Gene Name: glucagon receptor

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: gcgr assayed (4 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (6 sources): Abdominal pain, Abnormal biliary tract morphology, Cholelithiasis, Glucagonoma, Increased glucagon level, Neoplasm of the pancreas
Mouse (45 sources): abnormal exocrine gland morphology, abnormal kidney morphology, abnormal pancreatic acinar cell morphology, abnormal pancreatic alpha cell differentiation, abnormal pancreatic alpha cell morphology, abnormal pancreatic islet morphology, decreased abdominal adipose tissue amount, decreased brown adipose tissue amount, decreased carbon dioxide production, decreased circulating glucose level, decreased fasting circulating glucose level, decreased food intake, decreased gonadal fat pad weight, decreased interscapular fat pad weight, decreased litter size, decreased liver weight, decreased locomotor activity, decreased oxygen consumption, decreased susceptibility to diet-induced non-insulin dependent diabetes, decreased susceptibility to diet-induced obesity, decreased susceptibility to hepatic steatosis, decreased susceptibility to weight gain, decreased triglyceride level, endocrine/exocrine gland phenotype, enlarged pancreas, homeostasis/metabolism phenotype, improved glucose tolerance, increased bile salt level, increased body mass index, increased brain weight, increased glucagon secretion, increased glucagonoma incidence, increased insulin sensitivity, increased kidney weight, increased liver weight, increased pancreas weight, increased pancreatic alpha cell mass, increased pancreatic alpha cell number, increased pancreatic alpha cell proliferation, increased pancreatic beta cell mass, increased pancreatic beta cell proliferation, no abnormal phenotype detected, pancreatic islet hyperplasia, postnatal lethality, incomplete penetrance, prenatal lethality, incomplete penetrance [+]
View all ortholog results at Monarch