| Monarch Ortholog Phenotypes
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Human (33 sources):
Abnormal hair whorl,
Atrial septal defect,
Brachydactyly,
Cerebral atrophy,
Cleft palate,
Clinodactyly,
Delayed myelination,
Failure to thrive,
Generalized hypotonia,
Hearing impairment,
Hypertelorism,
Hypoplasia of the corpus callosum,
Hypoplasia of the maxilla,
Hypotonia,
Low-set ears,
Myoclonus,
Optic atrophy,
Patent foramen ovale,
Progressive microcephaly,
Ptosis,
Right ventricular hypertrophy,
Seizure,
Severe global developmental delay,
Short distal phalanx of finger,
Short nose,
Short stature,
Sloping forehead,
Small for gestational age,
Small nail,
Spastic tetraparesis,
Ventricular septal defect,
Vesicoureteral reflux,
Wide nose
[+]
|
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Mouse (6 sources):
abnormal cerebral cortex morphology,
hippocampal neuron degeneration,
immune system phenotype,
lethality at weaning, complete penetrance,
limb grasping,
preweaning lethality, incomplete penetrance
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View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.