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Summary Expression Phenotypes Gene Literature (9) GO Terms (22) Nucleotides (227) Proteins (66) Interactants (319) Wiki

dctn1     dynactin subunit 1

Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: dctn1 assayed (3 sources)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (32 sources): Abnormal lower motor neuron morphology, Abnormality of extrapyramidal motor function, Abnormality of metabolism/homeostasis, Apathy, Bradykinesia, Central hypoventilation, Dementia, Depression, Distal amyotrophy, Distal muscle weakness, [+]
Mouse (16 sources): abnormal gastrulation, abnormal neuromuscular synapse morphology, absent somites, decreased gastrocnemius weight, decreased motor neuron number, decreased vertical activity, embryonic growth arrest, embryonic lethality, complete penetrance, increased apoptosis, increased circulating creatinine level, [+]

View all ortholog results at Monarch