| Monarch Ortholog Phenotypes
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Human (22 sources):
Anemia,
Aortic valve stenosis,
Cholestasis,
Enlarged kidney,
Growth delay,
Hepatic fibrosis,
Hypertension,
Hypertrophic cardiomyopathy,
Hyposthenuria,
Nephronophthisis,
Patent ductus arteriosus,
Polycystic kidney dysplasia,
Polydipsia,
Polyuria,
Pulmonic stenosis,
Renal corticomedullary cysts,
Renal insufficiency,
Renal tubular atrophy,
Situs inversus totalis,
Stage 5 chronic kidney disease,
Tubular basement membrane disintegration,
Tubulointerstitial fibrosis
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Mouse (11 sources):
abnormal Mullerian duct morphology,
abnormal Wolffian duct morphology,
abnormal aortic valve morphology,
abnormal coronary sinus connection,
absent ductus venosus valve,
atrioventricular septal defect,
common atrioventricular valve,
dual inferior vena cava,
fetal growth retardation,
preweaning lethality, complete penetrance,
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.