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XB-GENEPAGE-6042120
cacna1h calcium channel, voltage-dependent, T type, alpha 1H subunit
Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology
covering anatomical, gene ontology, and neurobehavioral phenotypes.
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| abnormal neural tube closure (4 sources), abnormal calcium ion transport (1 source), abnormal closing of the posterior neural tube (1 source), abnormal development of brain (1 source), abnormally open neural tube (1 source), abnormal opening of the anterior neural tube (1 source) |
| Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.
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| Computed annotations: cacna1h assayed (5 sources) |
| Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting
the gene of interest.
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| Xla Wt + cacna1h MO (2 sources), Xla Wt + cacna1h MO (2 sources), Xla Wt + cacna1h MO (1 source), Xla Wt + cacna1h MO (1 source) |
| Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
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| Human (25 sources): Abnormal social behavior, Anxiety, Attention deficit hyperactivity disorder, Bilateral tonic-clonic seizure, Depression, Dyslexia, EEG with polyspike wave complexes, EEG with spike-wave complexes (2.5-3.5 Hz), EEG with spike-wave complexes (>3.5 Hz), Febrile seizure (within the age range of 3 months to 6 years), [+] |
| Mouse (9 sources): abnormal arteriole morphology, abnormal cartilage development, abnormal channel response, abnormal myocardial fiber morphology, abnormal tracheal cartilage morphology, abnormal vocalization, cardiac fibrosis, decreased body size, increased vasoconstriction |
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View all ortholog results at Monarch |