| Monarch Ortholog Phenotypes
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Human (20 sources):
Abnormal T-wave,
Abnormal autonomic nervous system physiology,
Abnormal cardiac exercise stress test,
Abnormality of prenatal development or birth,
Abnormality of the ear,
Atrial fibrillation,
Hypokalemia,
Palpitations,
Paroxysmal atrial fibrillation,
Permanent atrial fibrillation,
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Mouse (25 sources):
abnormal gastric chief cell morphology,
abnormal gastric parietal cell morphology,
abnormal stomach glandular epithelium morphology,
abnormal stomach glandular region morphology,
achlorhydria,
decreased circulating bilirubin level,
decreased circulating ferritin level,
decreased circulating iron level,
decreased digestive secretion,
decreased erythrocyte cell number,
decreased hematocrit,
decreased hemoglobin content,
decreased mean corpuscular hemoglobin,
decreased mean corpuscular volume,
decreased spleen iron level,
digestive/alimentary phenotype,
enlarged stomach,
gastric gland hyperplasia,
hematopoietic system phenotype,
homeostasis/metabolism phenotype,
hypochlorhydria,
increased adenoma incidence,
increased circulating erythropoietin level,
increased red blood cell distribution width,
increased stomach pH
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.