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Summary Expression Phenotypes Gene Literature (52) GO Terms (5) Nucleotides (56) Proteins (31) Interactants (45) Wiki

grik2     glutamate receptor, ionotropic, kainate 2

Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: grik2 assayed (5 sources)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (42 sources): Abnormal facial shape, Absent septum pellucidum, Autistic behavior, Cerebral atrophy, Cerebral visual impairment, Chorea, Cortical dysplasia, Delayed speech and language development, Depression, Dyskinesia, [+]
Mouse (12 sources): abnormal CNS synaptic transmission, abnormal contextual conditioning behavior, abnormal cued conditioning behavior, abnormal excitatory postsynaptic potential, abnormal glutamate-mediated receptor currents, abnormal long term potentiation, abnormal single cell response, decreased fear-related response, decreased paired-pulse facilitation, decreased susceptibility to pharmacologically induced seizures, [+]

View all ortholog results at Monarch