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XB-GENEPAGE-6070708
thrb thyroid hormone receptor, beta
Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology
covering anatomical, gene ontology, and neurobehavioral phenotypes.
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abnormal regulation of growth rate (1 source), increased width of head (1 source) |
Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.
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Manual annotations: thrb manipulated (1 source), thrb assayed (2 sources) |
Computed annotations: thrb assayed (2 sources) |
Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting
the gene of interest.
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Xtr Wt + thrb TALEN + mCherry (2 sources), Xtr Wt + TALEN thrb (1 source) |
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
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Human (11 sources): Attention deficit hyperactivity disorder, Delayed speech and language development, Elevated circulating thyroid-stimulating hormone concentration, Epiphyseal stippling, Goiter, Hearing impairment, Hyperthyroidism, Increased circulating free T3, Myopia, Proptosis, [+] |
Mouse (89 sources): abnormal Purkinje cell morphology, abnormal bone mineralization, abnormal cerebellar Purkinje cell layer, abnormal chondrocyte physiology, abnormal cochlea morphology, abnormal cochlear inner hair cell physiology, abnormal cochlear nerve compound action potential, abnormal cochlear outer hair cell physiology, abnormal cone electrophysiology, abnormal cranium morphology, [+] |
View all ortholog results at Monarch |