fosl1 Phenotypes

Summary

Expression

Phenotypes

XB-GENEPAGE-6257956

Gene Symbol: fosl1 Gene Name: FOS-like antigen 1

Anatomical Phenotypes Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
decreased cell population proliferation in cardiac myocyte (1 source), decreased cell population proliferation in heart (1 source)

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: fosl1 assayed (1 source)
Computed annotations: fosl1 assayed (8 sources)

Experiments (Reagents) These are short form descriptions of experiments using reagents targeting the gene of interest.
Xtr.Tg(mlc2:dnFosl1-eGFP)Qi + cardiac ventricle ablation (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (43 sources): abnormal bone mineralization, abnormal chorionic plate morphology, abnormal cranium morphology, abnormal embryonic erythrocyte morphology, abnormal long bone metaphysis morphology, abnormal neurocranium morphology, abnormal osteoblast physiology, abnormal parietal yolk sac morphology, abnormal placenta labyrinth morphology, abnormal placenta morphology, abnormal placenta vasculature, abnormal placental labyrinth vasculature morphology, abnormal skeleton physiology, abnormal vertebral body morphology, abnormal visceral endoderm morphology, abnormal visceral yolk sac endoderm morphology, abnormal visceral yolk sac morphology, abnormal vitelline vasculature morphology, cardiovascular system phenotype, decreased bone mass, decreased cardiac muscle contractility, decreased circulating alanine transaminase level, decreased circulating interleukin-6 level, decreased embryo size, decreased liver triglyceride level, decreased liver weight, decreased susceptibility to hepatic steatosis, decreased susceptibility to injury, embryonic lethality during organogenesis, complete penetrance, enhanced osteoblast differentiation, enlarged pericardium, increased bile salt level, increased bone mass, increased compact bone thickness, increased liver weight, increased sensitivity to induced morbidity/mortality, increased tumor incidence, liver/biliary system phenotype, no abnormal phenotype detected, osteosclerosis, premature death, prenatal lethality, complete penetrance, thick neurocranium [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (43 sources): abnormal bone mineralization, abnormal chorionic plate morphology, abnormal cranium morphology, abnormal embryonic erythrocyte morphology, abnormal long bone metaphysis morphology, abnormal neurocranium morphology, abnormal osteoblast physiology, abnormal parietal yolk sac morphology, abnormal placenta labyrinth morphology, abnormal placenta morphology, [+]