sh2d3c Phenotypes

XB-GENEPAGE-6258389

Gene Symbol: sh2d3c Gene Name: SH2 domain containing 3C

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: sh2d3c assayed (12 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (17 sources): abnormal axon extension, abnormal humoral immune response, abnormal leukocyte migration, abnormal marginal zone B cell physiology, abnormal olfactory bulb glomerular layer morphology, abnormal olfactory bulb layer morphology, abnormal olfactory bulb mitral cell layer morphology, abnormal olfactory nerve morphology, abnormal sensory neuron innervation pattern, abnormal sensory neuron morphology, absent gastric milk in neonates, decreased IgG1 level, decreased IgG2b level, decreased IgG3 level, decreased interleukin-6 secretion, decreased marginal zone B cell number, neonatal lethality, incomplete penetrance [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (17 sources): abnormal axon extension, abnormal humoral immune response, abnormal leukocyte migration, abnormal marginal zone B cell physiology, abnormal olfactory bulb glomerular layer morphology, abnormal olfactory bulb layer morphology, abnormal olfactory bulb mitral cell layer morphology, abnormal olfactory nerve morphology, abnormal sensory neuron innervation pattern, abnormal sensory neuron morphology, [+]