| Monarch Ortholog Phenotypes
|
Human (39 sources):
Abdominal pain,
Abnormal bleeding,
Abnormal granulocytopoietic cell morphology,
Acute promyelocytic leukemia,
Addictive alcohol use,
Anemia,
Anorexia,
Bone marrow hypercellularity,
Bone pain,
Bruising susceptibility,
Chronic infection,
Decreased total leukocyte count,
Decreased total neutrophil count,
Diffuse alveolar hemorrhage,
Disseminated intravascular coagulation,
Ecchymosis,
Epistaxis,
Exertional dyspnea,
Fatigue,
Fever,
Gangrene,
Gingival bleeding,
Gingival overgrowth,
Hematuria,
Hypofibrinogenemia,
Increased total leukocyte count,
Lymphadenopathy,
Metrorrhagia,
Moderate albuminuria,
Muscle weakness,
Oral cavity bleeding,
Pancytopenia,
Petechiae,
Productive cough,
Purpura,
Stomatitis,
Thrombocytopenia,
Vertigo,
Weight loss
[+]
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|
Mouse (6 sources):
abnormal mitotic spindle morphology,
absent fibroblast proliferation,
behavior/neurological phenotype,
cellular phenotype,
embryonic lethality during organogenesis, complete penetrance,
nervous system phenotype
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View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.