myh11 Phenotypes

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Phenotypes

Gene Literature (5)

Nucleotides (228)

Interactants (244)

XB-GENEPAGE-6459771

Gene Symbol: myh11 Gene Name: myosin heavy chain 11

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: myh11 assayed (2 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (72 sources): Abdominal aortic aneurysm, Abdominal distention, Abdominal pain, Abnormal cardiovascular system morphology, Abnormal iris pigmentation, Abnormal left ventricular function, Abnormal sternum morphology, Abnormality iris morphology, Abnormality of connective tissue, Abnormality of the gastrointestinal tract, Aganglionic megacolon, Aortic aneurysm, Aortic dissection, Aortic regurgitation, Aortic root aneurysm, Arachnodactyly, Ascending aortic dissection, Bicuspid aortic valve, Bruising susceptibility, Cardiomegaly, Carotid artery dilatation, Chest pain, Constipation, Coronary artery atherosclerosis, Cryptorchidism, Cutis marmorata, Cystic medial necrosis, Descending aortic dissection, Descending thoracic aorta aneurysm, Diarrhea, Dilatation of the cerebral artery, Dural ectasia, Dysphagia, Exertional dyspnea, Hemoptysis, High, narrow palate, Hydronephrosis, Hydroureter, Hypertelorism, Hypertension, Hypoperistalsis, Hypovolemia, Intestinal malrotation, Intestinal pseudo-obstruction, Ischemic stroke, Malnutrition, Megacystis, Microcolon, Mucoid extracellular matrix accumulation, Multicystic kidney dysplasia, Nausea and vomiting, Neoplasm of the heart, Omphalocele, Pancreatitis, Paroxysmal dyspnea, Patent ductus arteriosus, Peripheral arterial stenosis, Pes planus, Pneumothorax, Polyhydramnios, Prenatal maternal abnormality, Retrognathia, Scoliosis, Sepsis, Stroke, Subarachnoid hemorrhage, Tall stature, Transient ischemic attack, Umbilical hernia, Urinary retention, Vesicoureteral reflux, Vomiting [+]
Mouse (23 sources): abnormal airway resistance, abnormal cell adhesion, abnormal digestive system morphology, abnormal muscle contractility, abnormal sarcomere morphology, abnormal vascular regression, abnormal vascular smooth muscle physiology, abnormal vascular wound healing, cardiovascular system phenotype, decreased bronchoconstrictive response, decreased mean systemic arterial blood pressure, decreased vasoconstriction, dilated heart left ventricle, impaired contractility of urinary bladder detrusor smooth muscle, impaired smooth muscle contractility, increased cell proliferation, increased physiological sensitivity to xenobiotic, neonatal lethality, incomplete penetrance, postnatal lethality, complete penetrance, postnatal lethality, incomplete penetrance, premature death, slow postnatal weight gain, thin ventricular wall [+]
View all ortholog results at Monarch