Monarch Ortholog Phenotypes
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Human (40 sources):
Abnormality of pancreas physiology,
Abnormality of the endocrine system,
Abnormality of the urinary system,
Adrenocortical adenoma,
Angiofibromas,
Carcinoid tumor,
Carcinoma,
Cervix cancer,
Confetti-like hypopigmented macules,
Diarrhea,
Elevated circulating growth hormone concentration,
Elevated circulating parathyroid hormone level,
Episodic abdominal pain,
Erythema,
Extrahepatic cholestasis,
Fasting hyperinsulinemia,
Hypercalcemia,
Hyperinsulinemic hypoglycemia,
Hyperparathyroidism,
Increased circulating cortisol level,
Increased glucagon level,
Increased urinary cortisol level,
Insulinoma,
Neuroendocrine neoplasm,
Parathyroid adenoma,
Parathyroid carcinoma,
Parathyroid hyperplasia,
Peptic ulcer,
Pituitary adenoma,
Pituitary corticotropic cell adenoma,
Pituitary growth hormone cell adenoma,
Pituitary null cell adenoma,
Pituitary prolactin cell adenoma,
Pulmonary carcinoid tumor,
Renal angiomyolipoma,
Subcutaneous lipoma,
Testicular neoplasm,
Thymoma,
Thyroid adenoma,
Zollinger-Ellison syndrome
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Mouse (71 sources):
abnormal Muller cell morphology,
abnormal cell proliferation,
abnormal cerebral cortex morphology,
abnormal corpus luteum morphology,
abnormal definitive hematopoiesis,
abnormal epithalamus morphology,
abnormal eye electrophysiology,
abnormal fetal cardiomyocyte proliferation,
abnormal granulosa cell morphology,
abnormal hepatocyte morphology,
abnormal neuron differentiation,
abnormal organ of Corti morphology,
abnormal ovarian follicle morphology,
abnormal ovarian folliculogenesis,
abnormal pillar cell morphology,
abnormal pituitary intermediate lobe morphology,
abnormal prostate gland dorsolateral lobe morphology,
abnormal prostate gland physiology,
abnormal response/metabolism to endogenous compounds,
abnormal retina neuronal layer morphology,
abnormal retina outer limiting membrane morphology,
abnormal retina photoreceptor morphology,
abnormal retina pigment epithelium morphology,
abnormal tertiary ovarian follicle morphology,
abnormal thymus morphology,
abnormal uterus morphology,
absent corpus luteum,
adrenal medulla hyperplasia,
behavior/neurological phenotype,
decreased T cell proliferation,
decreased cell proliferation,
decreased incidence of tumors by chemical induction,
decreased keratinocyte proliferation,
decreased tumor incidence,
delayed wound healing,
disorganized retina layers,
enlarged prostate gland,
enlarged thymus,
heart hyperplasia,
increased T cell proliferation,
increased amacrine cell number,
increased body size,
increased brain weight,
increased brown adipose tissue amount,
increased cochlear hair cell number,
increased cochlear inner hair cell number,
increased cochlear outer hair cell number,
increased heart weight,
increased incidence of tumors by chemical induction,
increased inguinal fat pad weight,
increased kidney weight,
increased myocardial fiber number,
increased or absent threshold for auditory brainstem response,
increased organ of Corti supporting cell number,
increased parametrial fat pad weight,
increased pituitary adenoma incidence,
increased pituitary gland tumor incidence,
increased pituitary gland weight,
increased spleen weight,
increased thymocyte number,
increased thymus weight,
increased white fat cell number,
pituitary gland hyperplasia,
pituitary intermediate lobe hyperplasia,
premature death,
prolonged estrous cycle,
prolonged estrus,
small myocardial fiber,
spleen hyperplasia,
testicular hyperplasia,
thin ventricular wall
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View all ortholog results at Monarch
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