| Monarch Ortholog Phenotypes
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Human (9 sources):
Clubbing,
Cyanosis,
Failure to thrive,
Interstitial pneumonitis,
Intraalveolar phospholipid accumulation,
Recurrent respiratory infections,
Respiratory distress,
Tachypnea,
Tubulointerstitial fibrosis
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Mouse (16 sources):
abnormal bronchus epithelium morphology,
abnormal lung hysteresivity,
abnormal lung interstitium morphology,
abnormal lung vasculature morphology,
abnormal pulmonary alveolus epithelial cell morphology,
abnormal pulmonary alveolus morphology,
abnormal pulmonary elastic fiber morphology,
abnormal pulmonary interalveolar septum morphology,
abnormal surfactant physiology,
early reproductive senescence,
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.