Monarch Ortholog Phenotypes
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Mouse (41 sources):
abnormal cell proliferation,
abnormal crypts of Lieberkuhn morphology,
abnormal duodenum morphology,
abnormal gut-associated lymphoid tissue morphology,
abnormal intestinal epithelium morphology,
abnormal intestinal mucosa morphology,
abnormal intestinal peristalsis,
abnormal jejunum crypts of Lieberkuhn morphology,
abnormal jejunum morphology,
abnormal leukocyte migration,
abnormal marginal zone B cell morphology,
abnormal mesenteric lymph node morphology,
abnormal metallophilic macrophage morphology,
abnormal molar cusp morphology,
abnormal oropharynx morphology,
abnormal Peyer's patch follicle morphology,
abnormal spleen B cell follicle morphology,
abnormal spleen marginal sinus morphology,
abnormal spleen marginal zone macrophage morphology,
abnormal spleen periarteriolar lymphoid sheath morphology,
abnormal spleen primary B follicle morphology,
abnormal spleen red pulp morphology,
abnormal splenic cell ratio,
abnormal sublingual gland morphology,
abnormal tooth development,
absent marginal zone B cells,
absent spleen marginal zone,
decreased CD4-positive, alpha beta T cell number,
decreased molar number,
decreased Peyer's patch number,
decreased plasma cell number,
decreased spleen weight,
decreased spleen white pulp amount,
delayed intestine development,
increased enterocyte cell number,
intermingled spleen red and white pulp,
postnatal lethality, incomplete penetrance,
small cecum,
small Peyer's patches,
small spleen,
spleen atrophy
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