mfge8 Phenotypes

Phenotypes

XB-GENEPAGE-853464

Gene Symbol: mfge8 Gene Name: milk fat globule-EGF factor 8 protein

Anatomical Phenotypes Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
abnormal bending of anterior-posterior axis (1 source), abnormally ventrally curved tail (1 source)

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: mfge8 assayed (3 sources)

Experiments (Reagents) These are short form descriptions of experiments using reagents targeting the gene of interest.
Xtr Wt + mfge8 MO (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (22 sources): abnormal cell adhesion, abnormal epididymis morphology, abnormal involution of the mammary gland, abnormal lactation, abnormal mammary gland duct morphology, abnormal mammary gland growth during lactation, abnormal milk composition, abnormal physiological neovascularization, abnormal spleen B cell follicle morphology, decreased litter size, epididymis epithelium degeneration, hypolactation, immune system phenotype, impaired binding of sperm to zona pellucida, impaired macrophage phagocytosis, increased anti-double stranded DNA antibody level, increased spleen weight, increased spleen white pulp amount, mastitis, reduced male fertility, spermatic granuloma, spleen hyperplasia [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (22 sources): abnormal cell adhesion, abnormal epididymis morphology, abnormal involution of the mammary gland, abnormal lactation, abnormal mammary gland duct morphology, abnormal mammary gland growth during lactation, abnormal milk composition, abnormal physiological neovascularization, abnormal spleen B cell follicle morphology, decreased litter size, [+]