kmt2b Phenotypes

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Phenotypes

Gene Literature (6)

Nucleotides (187)

Interactants (62)

XB-GENEPAGE-853844

Gene Symbol: kmt2b Gene Name: lysine methyltransferase 2B

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (20 sources): Abnormality of eye movement, Astigmatism, Bulbous nose, Cognitive impairment, Craniofacial dystonia, Dysarthria, Dysphonia, Dystonia, Gait disturbance, Global developmental delay, Laryngeal dystonia, Microcephaly, Motor delay, Myoclonus, Oromandibular dystonia, Retrocollis, Short stature, Spasticity, Torticollis, obsolete Toe walking [+]
Mouse (40 sources): abnormal brown fat cell differentiation, abnormal dentate gyrus morphology, abnormal fetal cardiomyocyte morphology, abnormal heart echocardiography feature, abnormal heart tube morphology, abnormal hippocampus granule cell layer, abnormal inner ear canal morphology, abnormal motor capabilities/coordination/movement, abnormal object recognition memory, abnormal pinna reflex, absent head fold, absent somites, cardiovascular system phenotype, decreased IgG1 level, decreased brown adipose tissue amount, decreased coping response, decreased fetal cardiomyocyte proliferation, decreased follicular B cell number, decreased mature B cell number, decreased muscle weight, embryonic growth retardation, embryonic lethality between somite formation and embryo turning, complete penetrance, embryonic lethality during organogenesis, complete penetrance, flattened snout, hyporesponsive to tactile stimuli, immune system phenotype, impaired contextual conditioning behavior, impaired righting response, impaired spatial learning, increased B cell proliferation, increased germinal center B cell number, increased grooming behavior, increased spleen germinal center number, increased spleen germinal center size, increased vertical activity, neonatal lethality, complete penetrance, pericardial edema, short maxilla, short stride length, thin myocardium compact layer [+]
View all ortholog results at Monarch