abnormal liver sinusoid morphology, abnormal lung development, abnormal lung saccule morphology, abnormal lung vasculature morphology, abnormal myocardial fiber morphology, abnormal pancreatic beta cell morphology, abnormal pancreatic islet morphology, abnormal pulmonary alveolus epithelial cell morphology, abnormal respiratory conducting tube morphology, abnormal type II pneumocyte morphology, abnormal ventricle myocardium morphology, aortic hypertrophy, cardiovascular system phenotype, decreased heart left ventricle size, decreased hepatoblast number, decreased incidence of tumors by chemical induction, decreased liver tumor incidence, decreased mesenchymal cell proliferation involved in lung development, decreased myocardial fiber number, decreased pancreas weight, decreased pancreatic beta cell mass, decreased pancreatic beta cell proliferation, decreased surfactant secretion, decreased type I pneumocyte number, enlarged myocardial fiber, increased hepatocellular carcinoma incidence, increased incidence of tumors by chemical induction, increased lung adenoma incidence, increased pancreatic alpha cell number, lethality during fetal growth through weaning, incomplete penetrance, lethality throughout fetal growth and development, complete penetrance, lethality throughout fetal growth and development, incomplete penetrance, myocardial fiber disarray, neonatal lethality, incomplete penetrance, pancreas necrosis, pulmonary hyaline membrane formation, pulmonary vascular congestion, respiratory system phenotype, small alveolar lamellar bodies, small heart, small lung saccule, small pancreatic islets, thick heart valve cusps, thick lung-associated mesenchyme, thin myocardium, vascular smooth muscle hypertrophy, ventricular hypoplasia