abnormal cortical plate morphology, abnormal dendritic cell antigen presentation, abnormal digestive system morphology, abnormal embryonic growth/weight/body size, abnormal erythropoiesis, abnormal heart development, abnormal involution of the mammary gland, abnormal liver regeneration, abnormal long bone diaphysis morphology, abnormal megakaryocyte morphology, abnormal myocardial fiber physiology, abnormal osteoblast physiology, abnormal osteoclast differentiation, abnormal osteoclast morphology, abnormal osteoclast physiology, abnormal peritoneum morphology, abnormal synovial joint capsule morphology, abnormal thrombopoiesis, abnormal thymocyte activation, bowed fibula, cecum inflammation, decreased B-1a cell number, decreased IgG1 level, decreased IgG2a level, decreased IgG2b level, decreased blood urea nitrogen level, decreased body length, decreased body size, decreased circulating free fatty acids level, decreased common myeloid progenitor cell number, decreased diameter of femur, decreased double-positive T cell number, decreased embryo size, decreased hematopoietic stem cell number, decreased interferon-gamma secretion, decreased interleukin-4 secretion, decreased liver glycogen level, decreased osteoblast cell number, decreased physiological sensitivity to xenobiotic, decreased susceptibility to induced colitis, decreased thymocyte number, decreased trabecular bone thickness, embryonic lethality prior to tooth bud stage, embryonic lethality, incomplete penetrance, enlarged axillary lymph nodes, enlarged cervical lymph nodes, enlarged inguinal lymph nodes, enlarged mesenteric lymph nodes, enlarged stomach, failure of embryo implantation, growth/size/body region phenotype, increased CD4-positive, alpha beta T cell number, increased CD8-positive, alpha-beta T cell number, increased IgG1 level, increased IgG2a level, increased IgG2b level, increased activated T cell number, increased adenoma incidence, increased anti-double stranded DNA antibody level, increased anti-nuclear antigen antibody level, increased anti-single stranded DNA antibody level, increased autoantibody level, increased bone mineral content, increased bone mineralization, increased bone ossification, increased cell proliferation, increased circulating interleukin-6 level, increased circulating parathyroid hormone level, increased double-negative T cell number, increased interferon-gamma secretion, increased interleukin-6 secretion, increased neutrophil cell number, increased nucleated erythrocyte cell number, increased osteoblast cell number, increased osteoclast cell number, increased physiological sensitivity to xenobiotic, increased sensitivity to induced morbidity/mortality, increased sensitivity to xenobiotic induced morbidity/mortality, increased single-positive T cell number, increased stomach pH, increased susceptibility to endotoxin shock, increased susceptibility to induced arthritis, increased susceptibility to induced colitis, increased susceptibility to parasitic infection, increased trabecular bone thickness, lethality during fetal growth through weaning, complete penetrance, lethality throughout fetal growth and development, complete penetrance, liver/biliary system phenotype, neonatal lethality, complete penetrance, no abnormal phenotype detected, postnatal lethality, postnatal lethality, incomplete penetrance, premature death, preweaning lethality, complete penetrance, shortened RR interval, skeleton phenotype, spleen hyperplasia, thin ventricular wall